Ohio Man Claims Nexium Kidney Side Effects Concealed for Years

Published on September 23, 2016 by Sandy Liebhard

Text-Size:A A A+


A man from Ohio claims that AstraZeneca has concealed the kidney side effects associated with Nexium for years. His lawsuit, filed just last week in the U.S. District Court, Southern District of Ohio, asserts that he developed end stage renal disease (kidney failure) as a result of the company’s failure to provide appropriate warnings to patients and doctors.

According to the complaint, the plaintiff began taking Nexium in 2014, and was diagnosed with end stage renal disease in September of that year. As a result, he was left with severe and permanent injuries from Nexium.

“During the period in which Nexium has been sold in the United States, hundreds of reports of injury have been submitted to the FDA in association with ingestion of Nexium and other PPIs,” the lawsuit states. “Defendants have had notice of serious adverse health outcomes through case reports, clinical studies and post-market surveillance.”

Nexium Linked to Kidney Problems

Nexium and other proton pump inhibitors are used to treat peptic disorders related to excess stomach acid. They rank as some of the most popular drugs in the world, and are taken by millions. In recent years, however, proton pump inhibitors have been linked to a number of serious side effects, including fractures, vitamin B12 deficiency, low magnesium, dementia and heart attacks. Studies have also suggested that long-term use may harm the kidneys

In December 2014, the U.S. Food & Drug Administration required all manufacturers of prescription proton pump inhibitors to add mention of acute interstitial nephritis to their product labels. This sudden inflammation of the kidney tubules is often the result of an allergic reaction to a medication. Untreated, the disorder can lead to kidney disease and renal failure.

The following April, a study published in CMAJ Open linked proton pump inhibitors to a 3-fold increase in the risk for acute interstitial nephritis, as well as a 2.5 times higher risk of acute kidney injury.

The following April,  researchers writing in the Journal of the American Society of Nephrology reported that long-term users of proton pump inhibitors may be 96% more likely to develop kidney failure and 28% more likely to develop chronic kidney disease compared to patients using another class of heartburn drugs called H2-blockers. A study published in JAMA Internal Medicine in January also suggested that proton pump inhibitors might increase the risk of chronic kidney disease by as much as 50%.

Bernstein LiebhardLLP is offering free legal reviews to those who may have been harmed by Nexium. To learn more, please call (888) 726-4211.

Web Analytics